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Uniform gene expression in embryos is achieved by temporal averaging of transcription noise

Transcription is often stochastic. This is seemingly incompatible with the importance of gene expression during development. Here we show that during zebrafish embryogenesis, transcription activation is stochastic due to (1) genes acquiring transcriptional competence at different times in different...

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Detalles Bibliográficos
Autores principales: Stapel, L. Carine, Zechner, Christoph, Vastenhouw, Nadine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647934/
https://www.ncbi.nlm.nih.gov/pubmed/28903980
http://dx.doi.org/10.1101/gad.302935.117