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APC sets the Wnt tone necessary for cerebral cortical progenitor development

Adenomatous polyposis coli (APC) regulates the activity of β-catenin, an integral component of Wnt signaling. However, the selective role of the APC–β-catenin pathway in cerebral cortical development is unknown. Here we genetically dissected the relative contributions of APC-regulated β-catenin sign...

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Detalles Bibliográficos
Autores principales: Nakagawa, Naoki, Li, Jingjun, Yabuno-Nakagawa, Keiko, Eom, Tae-Yeon, Cowles, Martis, Mapp, Tavien, Taylor, Robin, Anton, E.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647938/
https://www.ncbi.nlm.nih.gov/pubmed/28916710
http://dx.doi.org/10.1101/gad.302679.117