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Polycomb directs timely activation of germline genes in spermatogenesis

During spermatogenesis, a large number of germline genes essential for male fertility are coordinately activated. However, it remains unknown how timely activation of this group of germline genes is accomplished. Here we show that Polycomb-repressive complex 1 (PRC1) directs timely activation of ger...

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Detalles Bibliográficos
Autores principales: Maezawa, So, Hasegawa, Kazuteru, Yukawa, Masashi, Sakashita, Akihiko, Alavattam, Kris G., Andreassen, Paul R., Vidal, Miguel, Koseki, Haruhiko, Barski, Artem, Namekawa, Satoshi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647939/
https://www.ncbi.nlm.nih.gov/pubmed/28924034
http://dx.doi.org/10.1101/gad.302000.117