Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element

Chromatin structure is tightly intertwined with transcription regulation. Here we compared the chromosomal architectures of fetal and adult human erythroblasts and found that, globally, chromatin structures and compartments A/B are highly similar at both developmental stages. At a finer scale, we de...

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Detalles Bibliográficos
Autores principales: Huang, Peng, Keller, Cheryl A., Giardine, Belinda, Grevet, Jeremy D., Davies, James O.J., Hughes, Jim R., Kurita, Ryo, Nakamura, Yukio, Hardison, Ross C., Blobel, Gerd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647940/
https://www.ncbi.nlm.nih.gov/pubmed/28916711
http://dx.doi.org/10.1101/gad.303461.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647940/
https://www.ncbi.nlm.nih.gov/pubmed/28916711
http://dx.doi.org/10.1101/gad.303461.117

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