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Two modes of targeting transposable elements by piRNA pathway in human testis

PIWI proteins and their partner small RNAs, termed piRNAs, are known to control transposable elements (TEs) in the germline. Here, we provide evidence that in humans this control is exerted in two different modes. On the one hand, production of piRNAs specifically targeting evolutionarily youngest T...

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Detalles Bibliográficos
Autores principales: Gainetdinov, Ildar, Skvortsova, Yulia, Kondratieva, Sofia, Funikov, Sergey, Azhikina, Tatyana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648030/
https://www.ncbi.nlm.nih.gov/pubmed/28842508
http://dx.doi.org/10.1261/rna.060939.117