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Cis-regulatory elements explain most of the mRNA stability variation across genes in yeast
The stability of mRNA is one of the major determinants of gene expression. Although a wealth of sequence elements regulating mRNA stability has been described, their quantitative contributions to half-life are unknown. Here, we built a quantitative model for Saccharomyces cerevisiae based on functio...
Autores principales: | Cheng, Jun, Maier, Kerstin C., Avsec, Žiga, Rus, Petra, Gagneur, Julien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648033/ https://www.ncbi.nlm.nih.gov/pubmed/28802259 http://dx.doi.org/10.1261/rna.062224.117 |
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