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The α-Tubulin gene TUBA1A in Brain Development: A Key Ingredient in the Neuronal Isotype Blend

Microtubules are dynamic cytoskeletal polymers that mediate numerous, essential functions such as axon and dendrite growth and neuron migration throughout brain development. In recent years, sequencing has revealed dominant mutations that disrupt the tubulin protein building blocks of microtubules....

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Detalles Bibliográficos
Autores principales: Aiken, Jayne, Buscaglia, Georgia, Bates, Emily A., Moore, Jeffrey K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648057/
https://www.ncbi.nlm.nih.gov/pubmed/29057214
http://dx.doi.org/10.3390/jdb5030008