Inhibition of early T cell cytokine production by arsenic trioxide occurs independently of Nrf2

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a stress-activated transcription factor that induces a variety of cytoprotective genes. Nrf2 also mediates immunosuppressive effects in multiple inflammatory models. Upon activation, Nrf2 dissociates from its repressor protein, Keap1, and translo...

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Detalles Bibliográficos
Autores principales: VanDenBerg, Kelly R., Freeborn, Robert A., Liu, Sheng, Kennedy, Rebekah C., Zagorski, Joseph W., Rockwell, Cheryl E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648109/
https://www.ncbi.nlm.nih.gov/pubmed/29049341
http://dx.doi.org/10.1371/journal.pone.0185579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648109/
https://www.ncbi.nlm.nih.gov/pubmed/29049341
http://dx.doi.org/10.1371/journal.pone.0185579

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