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Protein structural disorder of the envelope V3 loop contributes to the switch in human immunodeficiency virus type 1 cell tropism

Human immunodeficiency virus type 1 (HIV-1) envelope gp120 is partly an intrinsically disordered (unstructured/disordered) protein as it contains regions that do not fold into well-defined protein structures. These disordered regions play important roles in HIV’s life cycle, particularly, V3 loop-de...

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Detalles Bibliográficos
Autores principales: Jiang, Xiaowei, Feyertag, Felix, Robertson, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648111/
https://www.ncbi.nlm.nih.gov/pubmed/29049306
http://dx.doi.org/10.1371/journal.pone.0185790