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A kinase inhibitor library screen identifies novel enzymes involved in ototoxic damage to the murine organ of Corti
Ototoxicity is a significant side effect of a number of drugs, including the aminoglycoside antibiotics and platinum-based chemotherapeutic agents that are used to treat life-threatening illnesses. Although much progress has been made, the mechanisms that lead to ototoxic loss of inner ear sensory h...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648133/ https://www.ncbi.nlm.nih.gov/pubmed/29049311 http://dx.doi.org/10.1371/journal.pone.0186001 |