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A kinase inhibitor library screen identifies novel enzymes involved in ototoxic damage to the murine organ of Corti

Ototoxicity is a significant side effect of a number of drugs, including the aminoglycoside antibiotics and platinum-based chemotherapeutic agents that are used to treat life-threatening illnesses. Although much progress has been made, the mechanisms that lead to ototoxic loss of inner ear sensory h...

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Detalles Bibliográficos
Autores principales: Ryals, Matthew, Pak, Kwang, Jalota, Rahul, Kurabi, Arwa, Ryan, Allen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648133/
https://www.ncbi.nlm.nih.gov/pubmed/29049311
http://dx.doi.org/10.1371/journal.pone.0186001