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XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers

Cyclooxygenase (COX) is the rate-limiting enzyme in prostaglandins (PGs) biosynthesis. Previous studies indicate that COX-2, one of the isoforms of COX, is highly expressed in colon cancers and plays a key role in colon cancer carcinogenesis. Thus, searching for novel transcription factors regulatin...

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Detalles Bibliográficos
Autores principales: Zhang, Zhifeng, Zheng, Fufu, Yu, Zhenlong, Hao, Jiajiao, Chen, Miao, Yu, Wendan, Guo, Wei, Chen, Yiming, Huang, Wenlin, Duan, Zhijun, Deng, Wuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648251/
https://www.ncbi.nlm.nih.gov/pubmed/29049411
http://dx.doi.org/10.1371/journal.pone.0186900