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XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers
Cyclooxygenase (COX) is the rate-limiting enzyme in prostaglandins (PGs) biosynthesis. Previous studies indicate that COX-2, one of the isoforms of COX, is highly expressed in colon cancers and plays a key role in colon cancer carcinogenesis. Thus, searching for novel transcription factors regulatin...
Autores principales: | Zhang, Zhifeng, Zheng, Fufu, Yu, Zhenlong, Hao, Jiajiao, Chen, Miao, Yu, Wendan, Guo, Wei, Chen, Yiming, Huang, Wenlin, Duan, Zhijun, Deng, Wuguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648251/ https://www.ncbi.nlm.nih.gov/pubmed/29049411 http://dx.doi.org/10.1371/journal.pone.0186900 |
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