A Sarcoplasmic Reticulum Localized Protein Phosphatase Regulates Phospholamban Phosphorylation and Promotes Ischemia Reperfusion Injury in the Heart

Phospholamban (PLN) is a key regulator of sarcolemma calcium uptake in cardiomyocyte; its inhibitory activity to sarcolemma-endoplasmic reticulum calcium ATPase is regulated by phosphorylation. PLN hypophosphorylation is a common molecular feature in the failing heart. The current study provided evi...

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Detalles Bibliográficos
Autores principales: Akaike, Toru, Du, Na, Lu, Gang, Minamisawa, Susumu, Wang, Yibin, Ruan, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
PRECLINICAL RESEARCH
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648354/
https://www.ncbi.nlm.nih.gov/pubmed/29057374
http://dx.doi.org/10.1016/j.jacbts.2016.12.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648354/
https://www.ncbi.nlm.nih.gov/pubmed/29057374
http://dx.doi.org/10.1016/j.jacbts.2016.12.002

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