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Deletion of the NR4A nuclear receptor NOR1 in hematopoietic stem cells reduces inflammation but not abdominal aortic aneurysm formation
BACKGROUND: The NR4A3 orphan nuclear hormone receptor, NOR1, functions as a constitutively active transcription factor to regulate inflammation, proliferation, and cell survival during pathological vascular remodeling. Inflammatory processes represent key mechanisms leading to abdominal aortic aneur...
Autores principales: | Qing, Hua, Jones, Karrie L., Heywood, Elizabeth B., Lu, Hong, Daugherty, Alan, Bruemmer, Dennis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648424/ https://www.ncbi.nlm.nih.gov/pubmed/29047330 http://dx.doi.org/10.1186/s12872-017-0701-4 |
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