Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson’s case

[F-18]-AV-1451 is a novel positron emission tomography (PET) tracer with high affinity to neurofibrillary tau pathology in Alzheimer’s disease (AD). PET studies have shown increased tracer retention in patients clinically diagnosed with dementia of AD type and mild cognitive impairment in regions th...

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Detalles Bibliográficos
Autores principales: Marquié, Marta, Verwer, Eline E., Meltzer, Avery C., Kim, Sally Ji Who, Agüero, Cinthya, Gonzalez, Jose, Makaretz, Sara J., Siao Tick Chong, Michael, Ramanan, Prianca, Amaral, Ana C., Normandin, Marc D., Vanderburg, Charles R., Gomperts, Stephen N., Johnson, Keith A., Frosch, Matthew P., Gómez-Isla, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648451/
https://www.ncbi.nlm.nih.gov/pubmed/29047416
http://dx.doi.org/10.1186/s40478-017-0482-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648451/
https://www.ncbi.nlm.nih.gov/pubmed/29047416
http://dx.doi.org/10.1186/s40478-017-0482-0

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