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Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson’s case
[F-18]-AV-1451 is a novel positron emission tomography (PET) tracer with high affinity to neurofibrillary tau pathology in Alzheimer’s disease (AD). PET studies have shown increased tracer retention in patients clinically diagnosed with dementia of AD type and mild cognitive impairment in regions th...
Autores principales: | Marquié, Marta, Verwer, Eline E., Meltzer, Avery C., Kim, Sally Ji Who, Agüero, Cinthya, Gonzalez, Jose, Makaretz, Sara J., Siao Tick Chong, Michael, Ramanan, Prianca, Amaral, Ana C., Normandin, Marc D., Vanderburg, Charles R., Gomperts, Stephen N., Johnson, Keith A., Frosch, Matthew P., Gómez-Isla, Teresa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648451/ https://www.ncbi.nlm.nih.gov/pubmed/29047416 http://dx.doi.org/10.1186/s40478-017-0482-0 |
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