Loss of MKP-5 promotes myofiber survival by activating STAT3/Bcl-2 signaling during regenerative myogenesis

BACKGROUND: The mitogen-activated protein kinases (MAPKs) have been shown to be involved in regulating myofiber survival. In skeletal muscle, p38 MAPK and JNK are negatively regulated by MAPK phosphatase-5 (MKP-5). During muscle regeneration, MKP-5 is downregulated, thereby promoting p38 MAPK/JNK si...

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Detalles Bibliográficos
Autores principales: Min, Kisuk, Lawan, Ahmed, Bennett, Anton M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648478/
https://www.ncbi.nlm.nih.gov/pubmed/29047406
http://dx.doi.org/10.1186/s13395-017-0137-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648478/
https://www.ncbi.nlm.nih.gov/pubmed/29047406
http://dx.doi.org/10.1186/s13395-017-0137-7

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