Cargando…

Mapping eQTL by leveraging multiple tissues and DNA methylation

BACKGROUND: DNA methylation is an important tissue-specific epigenetic event that influences transcriptional regulation of gene expression. Differentially methylated CpG sites may act as mediators between genetic variation and gene expression, and this relationship can be exploited while mapping mul...

Descripción completa

Detalles Bibliográficos
Autores principales: Acharya, Chaitanya R., Owzar, Kouros, Allen, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648503/
https://www.ncbi.nlm.nih.gov/pubmed/29047346
http://dx.doi.org/10.1186/s12859-017-1856-9