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Mapping eQTL by leveraging multiple tissues and DNA methylation
BACKGROUND: DNA methylation is an important tissue-specific epigenetic event that influences transcriptional regulation of gene expression. Differentially methylated CpG sites may act as mediators between genetic variation and gene expression, and this relationship can be exploited while mapping mul...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648503/ https://www.ncbi.nlm.nih.gov/pubmed/29047346 http://dx.doi.org/10.1186/s12859-017-1856-9 |