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Unique N-terminal sequences in two Runx1 isoforms are dispensable for Runx1 function

BACKGROUND: The Runt-related transcription factors (Runx) are a family of evolutionarily conserved transcriptional regulators that play multiple roles in the developmental control of various cell types. Among the three mammalian Runx proteins, Runx1 is essential for definitive hematopoiesis and its...

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Detalles Bibliográficos
Autores principales: Nieke, Sebastian, Yasmin, Nighat, Kakugawa, Kiyokazu, Yokomizo, Tomomasa, Muroi, Sawako, Taniuchi, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648507/
https://www.ncbi.nlm.nih.gov/pubmed/29047338
http://dx.doi.org/10.1186/s12861-017-0156-y