A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma

BACKGROUND: The mitochondrial protein p32 is a validated therapeutic target of cancer overexpressed in glioma. Therapeutic targeting of p32 with monoclonal antibody or p32-binding LyP-1 tumor-homing peptide can limit tumor growth. However, these agents do not specifically target mitochondrial-locali...

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Detalles Bibliográficos
Autores principales: Yenugonda, Venkata, Nomura, Natsuko, Kouznetsova, Valentina, Tsigelny, Igor, Fogal, Valentina, Nurmemmedov, Elmar, Kesari, Santosh, Babic, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648515/
https://www.ncbi.nlm.nih.gov/pubmed/29047383
http://dx.doi.org/10.1186/s12967-017-1312-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648515/
https://www.ncbi.nlm.nih.gov/pubmed/29047383
http://dx.doi.org/10.1186/s12967-017-1312-7

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