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Frequency-dependent mobilization of heterogeneous pools of synaptic vesicles shapes presynaptic plasticity

The segregation of the readily releasable pool of synaptic vesicles (RRP) in sub-pools that are differentially poised for exocytosis shapes short-term plasticity. However, the frequency-dependent mobilization of these sub-pools is poorly understood. Using slice recordings and modeling of synaptic ac...

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Detalles Bibliográficos
Autores principales: Doussau, Frédéric, Schmidt, Hartmut, Dorgans, Kevin, Valera, Antoine M, Poulain, Bernard, Isope, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648531/
https://www.ncbi.nlm.nih.gov/pubmed/28990927
http://dx.doi.org/10.7554/eLife.28935