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Expression and Role of Voltage-Gated Sodium Channels in Human Dorsal Root Ganglion Neurons with Special Focus on Nav1.7, Species Differences, and Regulation by Paclitaxel

Voltage-gated sodium channels (Navs) play an important role in human pain sensation. However, the expression and role of Nav subtypes in native human sensory neurons are unclear. To address this issue, we obtained human dorsal root ganglion (hDRG) tissues from healthy donors. PCR analysis of seven D...

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Detalles Bibliográficos
Autores principales: Chang, Wonseok, Berta, Temugin, Kim, Yong Ho, Lee, Sanghoon, Lee, Seok-Yong, Ji, Ru-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648619/
https://www.ncbi.nlm.nih.gov/pubmed/28424991
http://dx.doi.org/10.1007/s12264-017-0132-3