Time-to-Seizure Modeling of Lacosamide Used in Monotherapy in Patients with Newly Diagnosed Epilepsy

OBJECTIVES: To quantify the relationship between exposure to lacosamide monotherapy and seizure probability, and to simulate the effect of changing the dose regimen. METHODS: Structural time-to-event models for dropouts (not because of a lack of efficacy) and seizures were developed using data from...

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Detalles Bibliográficos
Autores principales: Lindauer, Andreas, Laveille, Christian, Stockis, Armel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648747/
https://www.ncbi.nlm.nih.gov/pubmed/28290119
http://dx.doi.org/10.1007/s40262-017-0530-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648747/
https://www.ncbi.nlm.nih.gov/pubmed/28290119
http://dx.doi.org/10.1007/s40262-017-0530-8

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