CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing

U1 snRNP plays a critical role in 5ʹ-splice site recognition and is a frequent target of alternative splicing factors. These factors transiently associate with human U1 snRNP and are not amenable for structural studies, while their Saccharomyces cerevisiae (yeast) homologs are stable components of U...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xueni, Liu, Shiheng, Jiang, Jiansen, Zhang, Lingdi, Espinosa, Sara, Hill, Ryan C., Hansen, Kirk C., Zhou, Z. Hong, Zhao, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648754/
https://www.ncbi.nlm.nih.gov/pubmed/29051543
http://dx.doi.org/10.1038/s41467-017-01241-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648754/
https://www.ncbi.nlm.nih.gov/pubmed/29051543
http://dx.doi.org/10.1038/s41467-017-01241-9

Ejemplares similares