Cargando…
CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing
U1 snRNP plays a critical role in 5ʹ-splice site recognition and is a frequent target of alternative splicing factors. These factors transiently associate with human U1 snRNP and are not amenable for structural studies, while their Saccharomyces cerevisiae (yeast) homologs are stable components of U...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648754/ https://www.ncbi.nlm.nih.gov/pubmed/29051543 http://dx.doi.org/10.1038/s41467-017-01241-9 |