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Controlling for Confounding Effects in Single Cell RNA Sequencing Studies Using both Control and Target Genes

Single cell RNA sequencing (scRNAseq) technique is becoming increasingly popular for unbiased and high-resolutional transcriptome analysis of heterogeneous cell populations. Despite its many advantages, scRNAseq, like any other genomic sequencing technique, is susceptible to the influence of confoun...

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Detalles Bibliográficos
Autores principales: Chen, Mengjie, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648789/
https://www.ncbi.nlm.nih.gov/pubmed/29051597
http://dx.doi.org/10.1038/s41598-017-13665-w