Calmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers

Store-operated calcium entry (SOCE) is a major pathway for calcium ions influx into cells and has a critical role in various cell functions. Here we demonstrate that calcium-bound calmodulin (Ca(2+)-CaM) binds to the core region of activated STIM1. This interaction facilitates slow Ca(2+)-dependent...

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Detalles Bibliográficos
Autores principales: Li, Xin, Wu, Guangyan, Yang, Yin, Fu, Shijuan, Liu, Xiaofen, Kang, Huimin, Yang, Xue, Su, Xun-Cheng, Shen, Yuequan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648805/
https://www.ncbi.nlm.nih.gov/pubmed/29051492
http://dx.doi.org/10.1038/s41467-017-01135-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648805/
https://www.ncbi.nlm.nih.gov/pubmed/29051492
http://dx.doi.org/10.1038/s41467-017-01135-w

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