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Branched-chain amino acids and Alzheimer’s disease: a Mendelian randomization analysis

We conducted a two-sample Mendelian randomization study to test the hypothesis that raised plasma levels of the branched-chain amino acids isoleucine, leucine, and valine are associated with Alzheimer’s disease (AD). From a genome-wide association study of 16,596 individuals of European ancestry, we...

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Detalles Bibliográficos
Autores principales: Larsson, Susanna C., Markus, Hugh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648806/
https://www.ncbi.nlm.nih.gov/pubmed/29051501
http://dx.doi.org/10.1038/s41598-017-12931-1