Chronic antidepressant potentiates spontaneous activity of dorsal raphe serotonergic neurons by decreasing GABA(B) receptor-mediated inhibition of L-type calcium channels

Spontaneous activity of serotonergic neurons of the dorsal raphe nucleus (DRN) regulates mood and motivational state. Potentiation of serotonergic function is one of the therapeutic strategies for treatment of various psychiatric disorders, such as major depression, panic disorder and obsessive-comp...

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Detalles Bibliográficos
Autores principales: Asaoka, Nozomi, Nishitani, Naoya, Kinoshita, Haruko, Kawai, Hiroyuki, Shibui, Norihiro, Nagayasu, Kazuki, Shirakawa, Hisashi, Nakagawa, Takayuki, Kaneko, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648823/
https://www.ncbi.nlm.nih.gov/pubmed/29051549
http://dx.doi.org/10.1038/s41598-017-13599-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648823/
https://www.ncbi.nlm.nih.gov/pubmed/29051549
http://dx.doi.org/10.1038/s41598-017-13599-3

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