Effect of Specific Mutations in Cd300 Complexes Formation; Potential Implication of Cd300f in Multiple Sclerosis

Herein, we have used bioinformatics tools to predict five clusters defining ligand-binding sites on the extracellular domain of human CD300b receptor, presumably involved in the formation of both homodimers and heterodimers with other CD300 family members. Site-directed mutagenesis revealed residues...

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Detalles Bibliográficos
Autores principales: Martínez-Barriocanal, Águeda, Arcas-García, Andrea, Magallon-Lorenz, Miriam, Ejarque-Ortíz, Aroa, Negro-Demontel, María Luciana, Comas-Casellas, Emma, Schwartz, Simo, Malhotra, Sunny, Montalban, Xavier, Peluffo, Hugo, Martín, Margarita, Comabella, Manuel, Sayós, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648872/
https://www.ncbi.nlm.nih.gov/pubmed/29051512
http://dx.doi.org/10.1038/s41598-017-12881-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648872/
https://www.ncbi.nlm.nih.gov/pubmed/29051512
http://dx.doi.org/10.1038/s41598-017-12881-8

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