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Synchrotron radiation circular dichroism spectroscopy reveals structural divergences in HDL-bound apoA-I variants

Apolipoprotein A-I (apoA-I) in high-density lipoprotein (HDL) provides cardiovascular protection. Synchrotron radiation circular dichroism (SRCD) spectroscopy was used to analyze the dynamic solution structure of the apoA-I protein in the apo- and HDL-states and the protein structure conversion in H...

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Detalles Bibliográficos
Autores principales: Giudice, Rita Del, Nilsson, Oktawia, Domingo-Espín, Joan, Lagerstedt, Jens O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648894/
https://www.ncbi.nlm.nih.gov/pubmed/29051568
http://dx.doi.org/10.1038/s41598-017-13878-z