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Gamma Interferon Mediates Experimental Cerebral Malaria by Signaling within Both the Hematopoietic and Nonhematopoietic Compartments

Experimental cerebral malaria (ECM) is a gamma interferon (IFN-γ)-dependent syndrome. However, whether IFN-γ promotes ECM through direct and synergistic targeting of multiple cell populations or by acting primarily on a specific responsive cell type is currently unknown. Here, using a panel of cell-...

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Detalles Bibliográficos
Autores principales: Villegas-Mendez, Ana, Strangward, Patrick, Shaw, Tovah N., Rajkovic, Ivana, Tosevski, Vinko, Forman, Ruth, Muller, Werner, Couper, Kevin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649021/
https://www.ncbi.nlm.nih.gov/pubmed/28874445
http://dx.doi.org/10.1128/IAI.01035-16