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Negative genic switch of HER-2 in the primary tumor instead of the synchronous metastatic nodal lesions after neoadjuvant chemotherapy in a patient with primary HER2-positive breast cancer

BACKGROUND: A few retrospective studies have indicated that neoadjuvant chemotherapy (NAC) in breast cancer may change biomarker profiles of the primary tumor. Little is known about the status of HER-2 gene of the synchronous nodal metastases when that of the residual tumor undergoes negative conver...

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Detalles Bibliográficos
Autores principales: Chen, Hao-ran, Wu, Yu-tuan, Yu, Qiu-bo, Yang, Ya-ying, Wei, Yu-xian, Li, Hong-yuan, Wu, Kai-nan, Kong, Ling-quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649047/
https://www.ncbi.nlm.nih.gov/pubmed/29052527
http://dx.doi.org/10.1186/s12957-017-1255-8