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Breathing new life into an old target: pulmonary disease drugs for Parkinson’s disease therapy

Increases in α-synuclein protein expression are suspected to increase the risk of the development of Parkinson’s disease (PD). A recent study has demonstrated that β2-adrenergic receptor (β2AR) agonists decrease histone acetylation in the α-synuclein gene and suppress transcription. Coupled with the...

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Detalles Bibliográficos
Autores principales: Abdelmotilib, Hisham, West, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649055/
https://www.ncbi.nlm.nih.gov/pubmed/29052536
http://dx.doi.org/10.1186/s13073-017-0483-4