A method to reduce ancestry related germline false positives in tumor only somatic variant calling

BACKGROUND: Significant clinical and research applications are driving large scale adoption of individualized tumor sequencing in cancer in order to identify tumors-specific mutations. When a matched germline sample is available, somatic mutations may be identified using comparative callers. However...

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Detalles Bibliográficos
Autores principales: Halperin, Rebecca F., Carpten, John D., Manojlovic, Zarko, Aldrich, Jessica, Keats, Jonathan, Byron, Sara, Liang, Winnie S., Russell, Megan, Enriquez, Daniel, Claasen, Ana, Cherni, Irene, Awuah, Baffour, Oppong, Joseph, Wicha, Max S., Newman, Lisa A., Jaigge, Evelyn, Kim, Seungchan, Craig, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649057/
https://www.ncbi.nlm.nih.gov/pubmed/29052513
http://dx.doi.org/10.1186/s12920-017-0296-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649057/
https://www.ncbi.nlm.nih.gov/pubmed/29052513
http://dx.doi.org/10.1186/s12920-017-0296-8

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