Cargando…

Dose and Time Dependencies in Stress Pathway Responses during Chemical Exposure: Novel Insights from Gene Regulatory Networks

Perturbation of biological networks is often observed during exposure to xenobiotics, and the identification of disturbed processes, their dynamic traits, and dose–response relationships are some of the current challenges for elucidating the mechanisms determining adverse outcomes. In this scenario,...

Descripción completa

Detalles Bibliográficos
Autores principales: Souza, Terezinha M., Kleinjans, Jos C. S., Jennen, Danyel G. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649202/
https://www.ncbi.nlm.nih.gov/pubmed/29085386
http://dx.doi.org/10.3389/fgene.2017.00142