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Macropinocytosis: A Metabolic Adaptation to Nutrient Stress in Cancer

Oncogenic mutations, such as Ras mutations, drive not only enhanced proliferation but also the metabolic adaptations that confer to cancer cells the ability to sustain cell growth in a harsh tumor microenvironment. These adaptations might represent metabolic vulnerabilities that can be exploited to...

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Detalles Bibliográficos
Autores principales: Recouvreux, Maria Victoria, Commisso, Cosimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649207/
https://www.ncbi.nlm.nih.gov/pubmed/29085336
http://dx.doi.org/10.3389/fendo.2017.00261