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Peripheral Leukocytosis Is Inversely Correlated with Intratumoral CD8+ T-Cell Infiltration and Associated with Worse Outcome after Chemoradiotherapy in Anal Cancer

Peripheral blood leukocytosis has been implicated in promoting tumor progression leading to worse survival, but the mechanisms behind this phenomenon remain unexplored. Here, we examined the prognostic role of pretreatment white blood cell (WBC) count and clinicopathologic parameters in the context...

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Detalles Bibliográficos
Autores principales: Martin, Daniel, Rödel, Franz, Winkelmann, Ria, Balermpas, Panagiotis, Rödel, Claus, Fokas, Emmanouil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649213/
https://www.ncbi.nlm.nih.gov/pubmed/29085358
http://dx.doi.org/10.3389/fimmu.2017.01225