Addition of exogenous sodium palmitate increases the IAPP/insulin mRNA ratio via GPR40 in human EndoC-βH1 cells

BACKGROUND: Enhanced IAPP production may contribute to islet amyloid formation in type 2 diabetes. The objective of this study was to determine the effects of the saturated fatty acid palmitate on IAPP levels in human β-cells. METHODS: EndoC-βH1 cells and human islets were cultured in the presence o...

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Detalles Bibliográficos
Autores principales: Krizhanovskii, Camilla, Fred, Rikard G., Oskarsson, Marie E., Westermark, Gunilla T., Welsh, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649320/
https://www.ncbi.nlm.nih.gov/pubmed/28980863
http://dx.doi.org/10.1080/03009734.2017.1368745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649320/
https://www.ncbi.nlm.nih.gov/pubmed/28980863
http://dx.doi.org/10.1080/03009734.2017.1368745

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