Compensatory mutations improve general permissiveness to antibiotic resistance plasmids

Horizontal gene transfer mediated by broad-host-range plasmids is an important mechanism of antibiotic resistance spread. While not all bacteria maintain plasmids equally well, plasmid persistence can improve over time, yet no general evolutionary mechanisms have emerged. Our goal was to identify th...

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Detalles Bibliográficos
Autores principales: Loftie-Eaton, Wesley, Bashford, Kelsie, Quinn, Hannah, Dong, Kieran, Millstein, Jack, Hunter, Samuel, Thomason, Maureen K., Merrikh, Houra, Ponciano, Jose M., Top, Eva M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649373/
https://www.ncbi.nlm.nih.gov/pubmed/29046540
http://dx.doi.org/10.1038/s41559-017-0243-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649373/
https://www.ncbi.nlm.nih.gov/pubmed/29046540
http://dx.doi.org/10.1038/s41559-017-0243-2

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