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Compensatory mutations improve general permissiveness to antibiotic resistance plasmids
Horizontal gene transfer mediated by broad-host-range plasmids is an important mechanism of antibiotic resistance spread. While not all bacteria maintain plasmids equally well, plasmid persistence can improve over time, yet no general evolutionary mechanisms have emerged. Our goal was to identify th...
Autores principales: | Loftie-Eaton, Wesley, Bashford, Kelsie, Quinn, Hannah, Dong, Kieran, Millstein, Jack, Hunter, Samuel, Thomason, Maureen K., Merrikh, Houra, Ponciano, Jose M., Top, Eva M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649373/ https://www.ncbi.nlm.nih.gov/pubmed/29046540 http://dx.doi.org/10.1038/s41559-017-0243-2 |
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