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Tp53 gene mediates distinct dopaminergic neuronal damage in different dopaminergic neurotoxicant models

Tp53, a stress response gene, is involved in diverse cell death pathways and its activation is implicated in the pathogenesis of Parkinson's disease. However, whether the neuronal Tp53 protein plays a direct role in regulating dopaminergic (DA) neuronal cell death or neuronal terminal damage in...

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Detalles Bibliográficos
Autores principales: Lu, Tao, Kim, Paul, Luo, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649453/
https://www.ncbi.nlm.nih.gov/pubmed/29089978
http://dx.doi.org/10.4103/1673-5374.215243