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The involvement of E6, p53, p16, MDM2 and Gal-3 in the clinical outcome of patients with cervical cancer
High-risk human papilloma virus (HPV) is the leading cause of cervical cancer. HPV oncogenes are responsible for the development of malignancy, and the E6 oncoprotein that HPV expresses induces the degradation of tumour suppressor protein p53 (p53). This degradation leads to the upregulation of p16;...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649573/ https://www.ncbi.nlm.nih.gov/pubmed/29085443 http://dx.doi.org/10.3892/ol.2017.6752 |