The involvement of E6, p53, p16, MDM2 and Gal-3 in the clinical outcome of patients with cervical cancer

High-risk human papilloma virus (HPV) is the leading cause of cervical cancer. HPV oncogenes are responsible for the development of malignancy, and the E6 oncoprotein that HPV expresses induces the degradation of tumour suppressor protein p53 (p53). This degradation leads to the upregulation of p16;...

Descripción completa

Detalles Bibliográficos
Autores principales: Stiasny, Annika, Freier, Christoph P., Kuhn, Christina, Schulze, Sandra, Mayr, Doris, Alexiou, Christoph, Janko, Christina, Wiest, Irmi, Dannecker, Christian, Jeschke, Udo, Kost, Bernd P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649573/
https://www.ncbi.nlm.nih.gov/pubmed/29085443
http://dx.doi.org/10.3892/ol.2017.6752

Ejemplares similares

Ejemplares similares