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HLA-mediated tumor escape mechanisms that may impair immunotherapy clinical outcomes via T-cell activation

Although the immune system provides protection from cancer by means of immunosurveillance, which serves a major function in eliminating cancer cells, it may also lead to cancer immunoediting, molding tumor immunogenicity. Cancer cells exploit several molecular mechanisms to thwart immune-mediated de...

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Detalles Bibliográficos
Autor principal: Rodríguez, Josefa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649701/
https://www.ncbi.nlm.nih.gov/pubmed/29085437
http://dx.doi.org/10.3892/ol.2017.6784