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GATA2 deficiency and related myeloid neoplasms

The GATA2 gene codes for a hematopoietic transcription factor that through its two zinc fingers (ZF) can occupy GATA-DNA motifs in a countless number of genes. It is crucial for the proliferation and maintenance of hematopoietic stem cells. During the past 5 years, germline heterozygous mutations in...

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Detalles Bibliográficos
Autores principales: Wlodarski, Marcin W., Collin, Matthew, Horwitz, Marshall S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650112/
https://www.ncbi.nlm.nih.gov/pubmed/28637621
http://dx.doi.org/10.1053/j.seminhematol.2017.05.002