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GPR40 partial agonists and AgoPAMs: Differentiating effects on glucose and hormonal secretions in the rodent
GPR40 agonists are effective antidiabetic agents believed to lower glucose through direct effects on the beta cell to increase glucose stimulated insulin secretion. However, not all GPR40 agonists are the same. Partial agonists lower glucose through direct effects on the pancreas, whereas GPR40 AgoP...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650142/ https://www.ncbi.nlm.nih.gov/pubmed/29053717 http://dx.doi.org/10.1371/journal.pone.0186033 |