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3D morphological analysis of the mouse cerebral vasculature: Comparison of in vivo and ex vivo methods

Ex vivo 2-photon fluorescence microscopy (2PFM) with optical clearing enables vascular imaging deep into tissue. However, optical clearing may also produce spherical aberrations if the objective lens is not index-matched to the clearing material, while the perfusion, clearing, and fixation procedure...

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Detalles Bibliográficos
Autores principales: Steinman, Joe, Koletar, Margaret M., Stefanovic, Bojana, Sled, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650181/
https://www.ncbi.nlm.nih.gov/pubmed/29053753
http://dx.doi.org/10.1371/journal.pone.0186676