Sulforaphane reduces YAP/∆Np63α signaling to reduce cancer stem cell survival and tumor formation

Epidermal squamous cell carcinoma (SCC) is among the most common cancers. SCC can be treated by surgical excision, but recurrence of therapy-resistant disease is a major problem. We recently showed that YAP1, the Hippo signaling transcription adaptor protein, and ∆Np63α, a key epidermal stem cell su...

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Detalles Bibliográficos
Autores principales: Fisher, Matthew L., Ciavattone, Nicholas, Grun, Daniel, Adhikary, Gautam, Eckert, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650271/
https://www.ncbi.nlm.nih.gov/pubmed/29088716
http://dx.doi.org/10.18632/oncotarget.20562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650271/
https://www.ncbi.nlm.nih.gov/pubmed/29088716
http://dx.doi.org/10.18632/oncotarget.20562

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